Glycobiology of the Immune System and Disease

Glycobiology of the Immune System and Disease explores the integration of state-of-the-art glycobiology and immunology to raise awareness of the multifaceted roles of glycans and lectins in the immune system. Glycobiology is a rapidly growing field in biology, with relevance to biomedicine, biotechnology and basic research. Considering the central role that glycans play in immune interactions, glycoproteins and carbohydrates are becoming the targets of next-generation therapeutics, vaccines and diagnostics. Programmed remodeling of host glycans can modulate infection, autoimmunity, and cancer, while microbial glycoconjugates can serve as canonical innate receptor agonists that induce B cell and T cell activation. This important reference investigates microbial and mammalian glycans and their protein-binding partners (lectins) and shows the role they play in all innate and adaptive immune responses. With its comprehensive overview of the field, this is an important resource for academicians, graduate and post graduate students as well as professors and faculty in the field of research in glycobiology and immunology. Provides the first book on the glycobiology of the immune system Gives insights on the glycobiology of the epidemic and pandemic causing virus H1N1/H5N1, Coronavirus and COVID-19 Highlights the importance of glycobiology and its probable role in generating therapy for viral infections Provides up-to-date and accessible information for beginners in glycoimmunology and for readers with an interest in infectious diseases and host response