Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies. This book should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists.
| Serija: | Advances in Experimental Medicine and Biology |
| Leidėjas: | Springer US |
| Išleidimo metai: | 2001 |
| Knygos puslapių skaičius: | 156 |
| ISBN-10: | 0306465701 |
| ISBN-13: | 9780306465703 |
| Formatas: | Knyga kietu viršeliu |
| Kalba: | Anglų |
| Žanras: | Immunology |
Parašykite atsiliepimą apie „Mechanisms of Lymphocyte Activation and Immune Regulation VIII: Autoimmunity 2000 and Beyond“
